view release on metacpan or  search on metacpan

README  view on Meta::CPAN

        especially good at:

        * Finding rearrangements and recombinations: the primary author
        claims that last-split does that more rigorously than anything else.
        * Finding DNA-versus-protein related regions, especially protein
        fossils. * Unusual data, e.g. AT-rich DNA, because we can fit
        parameters to the data and calculate significance. * Sensitive
        DNA-DNA search, due to fitting, sensitive seeding, and calculating
        significance.

        It can also: indicate the confidence/uncertainty of each column in
        an alignment, and use sequence quality data in a rigorous fashion.

    *   last-split-pe
        <https://bitbucket.org/splitpairedend/last-split-pe/wiki/Home>

        last-split-pe is a method that can split-align a short DNA read to a
        reference genome. It achieves high accuracy by combining
        probabilistic alignments with information from paired-end reads.

    *   Alien

lib/Alien/SeqAlignment/last.pm  view on Meta::CPAN

* Finding rearrangements and recombinations: the primary author claims 
that last-split does that more rigorously than anything else.
* Finding DNA-versus-protein related regions, especially protein
fossils.
* Unusual data, e.g. AT-rich DNA, because we can fit parameters to
the data and calculate significance.
* Sensitive DNA-DNA search, due to fitting, sensitive seeding, and
calculating significance.

It can also: indicate the confidence/uncertainty of each column in an
alignment, and use sequence quality data in a rigorous fashion.

=item * L<last-split-pe|https://bitbucket.org/splitpairedend/last-split-pe/wiki/Home>

last-split-pe is a method that can split-align a short DNA read to a 
reference genome. It achieves high accuracy by combining probabilistic 
alignments with information from paired-end reads.

=item * L<Alien>