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</source>
<!-- List of experiments, keyed to experimentDescription, e.g. 617684 -->
<experimentList>
<experimentDescription id="EBI-617684">
<names>
<shortLabel>eyckerman-2001-1</shortLabel>
<fullName>Design and application of a cytokine-receptor-based interaction trap.</fullName>
</names>
<bibref>
<xref>
<primaryRef db="pubmed" id="11781573"/>
</xref>
</bibref>
<xref>
<primaryRef db="intact" id="EBI-617684" secondary="eyckerman-2001-1"/>
<secondaryRef db="newt" id="10090" secondary="mouse"/>
<secondaryRef db="newt" id="10633" secondary="sv40"/>
<secondaryRef db="newt" id="9606" secondary="human"/>
</xref>
<hostOrganism ncbiTaxId="9606">
<names>
<shortLabel>human-293t</shortLabel>
<fullName>Homo sapiens 293 cells transformed with SV40 large T antigen</fullName>
</names>
<cellType>
<names>
<shortLabel>293t</shortLabel>
<fullName>293 cells expressing SV40 large T antigen.</fullName>
</names>
<xref>
<primaryRef db="pubmed" id="3031469"/>
<secondaryRef db="cabri" id="ICLC HTL04001"/>
</xref>
</cellType>
</hostOrganism>
<interactionDetection>
<names>
<shortLabel>mappit</shortLabel>
<fullName>mammalian protein protein interaction trap</fullName>
</names>
<xref>
<primaryRef db="psi-mi" id="MI:0231"/>
<secondaryRef db="pubmed" id="12853652"/>
</xref>
</interactionDetection>
<participantDetection>
<names>
<shortLabel>predetermined</shortLabel>
<fullName>predetermined participant</fullName>
</names>
<xref>
<primaryRef db="psi-mi" id="MI:0396"/>
<secondaryRef db="pubmed" id="7940758"/>
<secondaryRef db="pubmed" id="14755292"/>
</xref>
</participantDetection>
<attributeList>
<attribute name="exp-modification">MAPPIT bait construct - a chimeric cytokine receptor composed of the extracellular region of homodimeric EpoR, fused to the transmembrane and cytosolic domains of the leptin receptor wherein all the tyr...
<attribute name="figure-legend">2b, 2c, 5</attribute>
<attribute name="contact-email">jan.tavernier@ugent.be</attribute>
<attribute name="author-list">Eyckerman S., Verhee A., der Heyden JV., Lemmens I., Ostade XV., Vandekerckhove J., Tavernier J.</attribute>
</attributeList>
</experimentDescription>
</experimentList>
<!-- interactorList, keyed to proteinInteractor, e.g. EBI-617698 -->
<interactorList>
<proteinInteractor id="EBI-617698">
<names>
<shortLabel>tala_sv40</shortLabel>
<fullName>Large T antigen</fullName>
</names>
<xref>
<primaryRef db="uniprotkb" id="P03070" secondary="tala_sv40" version="SP_48"/>
<secondaryRef db="interpro" id="IPR001623" secondary="DnaJ_N"/>
<secondaryRef db="interpro" id="IPR010932" secondary="Polyoma_lg_T_C"/>
<secondaryRef db="interpro" id="IPR003133" secondary="T_Ag_DNA_bind"/>
<secondaryRef db="intact" id="EBI-617698" secondary="tala_sv40"/>
</xref>
<organism ncbiTaxId="10633">
<names>
<shortLabel>sv40</shortLabel>
<fullName>Simian virus 40</fullName>
</names>
</organism>
<sequence>MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADSQHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKE...
</proteinInteractor>
<proteinInteractor id="EBI-474016">
<names>
<shortLabel>p53_mouse</shortLabel>
<fullName>Cellular tumor antigen p53</fullName>
</names>
<xref>
<primaryRef db="uniprotkb" id="P02340" secondary="p53_mouse" version="SP_48"/>
<secondaryRef db="go" id="GO:0005829" secondary="C:cytosol"/>
<secondaryRef db="go" id="GO:0005739" secondary="C:mitochondrion"/>
<secondaryRef db="go" id="GO:0005730" secondary="C:nucleolus"/>
<secondaryRef db="go" id="GO:0005524" secondary="F:ATP binding"/>
<secondaryRef db="go" id="GO:0005507" secondary="F:copper ion binding"/>
<secondaryRef db="go" id="GO:0000739" secondary="F:DNA strand annealing activit"/>
<secondaryRef db="go" id="GO:0005515" secondary="F:protein binding"/>
<secondaryRef db="go" id="GO:0003700" secondary="F:transcription factor activit"/>
<secondaryRef db="go" id="GO:0006915" secondary="P:apoptosis"/>
<secondaryRef db="go" id="GO:0006284" secondary="P:base-excision repair"/>
<secondaryRef db="go" id="GO:0008635" secondary="P:caspase activation via cytoc"/>
<secondaryRef db="go" id="GO:0007569" secondary="P:cell aging"/>
<secondaryRef db="go" id="GO:0007050" secondary="P:cell cycle arrest"/>
<secondaryRef db="go" id="GO:0030154" secondary="P:cell differentiation"/>
<secondaryRef db="go" id="GO:0042771" secondary="P:DNA damage response, signal"/>
<secondaryRef db="go" id="GO:0043066" secondary="P:negative regulation of apopt"/>
<secondaryRef db="go" id="GO:0030308" secondary="P:negative regulation of cell"/>
<secondaryRef db="go" id="GO:0008156" secondary="P:negative regulation of DNA r"/>
<secondaryRef db="go" id="GO:0048147" secondary="P:negative regulation of fibro"/>
<secondaryRef db="go" id="GO:0006289" secondary="P:nucleotide-excision repair"/>
<secondaryRef db="go" id="GO:0000060" secondary="P:protein-nucleus import, tran"/>
<secondaryRef db="go" id="GO:0042127" secondary="P:regulation of cell prolifera"/>
<secondaryRef db="go" id="GO:0006355" secondary="P:regulation of transcription,"/>
<secondaryRef db="go" id="GO:0006974" secondary="P:response to DNA damage stimu"/>
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