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<shortLabel>epor_human</shortLabel>
<fullName>Erythropoietin receptor precursor</fullName>
</names>
<xref>
<primaryRef db="uniprotkb" id="P19235" secondary="epor_human" version="SP_48"/>
<secondaryRef db="go" id="GO:0005887" secondary="C:integral to plasma membrane"/>
<secondaryRef db="go" id="GO:0004900" secondary="F:erythropoietin receptor acti"/>
<secondaryRef db="go" id="GO:0007165" secondary="P:signal transduction"/>
<secondaryRef db="interpro" id="IPR002996" secondary="Cytkn_recept_B/G"/>
<secondaryRef db="interpro" id="IPR009167" secondary="EPO_receptor"/>
<secondaryRef db="interpro" id="IPR003961" secondary="FN_III"/>
<secondaryRef db="interpro" id="IPR008957" secondary="FN_III-like"/>
<secondaryRef db="interpro" id="IPR003528" secondary="HemptreceptL_F1"/>
<secondaryRef db="uniprotkb" id="Q15443" secondary="epor_human" version="SP_48"/>
<secondaryRef db="intact" id="EBI-617321" secondary="epor_human"/>
</xref>
<organism ncbiTaxId="9606">
<names>
<shortLabel>human</shortLabel>
<fullName>Homo sapiens</fullName>
</names>
</organism>
<sequence>MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSF...
</proteinInteractor>
<proteinInteractor id="EBI-617489">
<names>
<shortLabel>cish_mouse</shortLabel>
<fullName>Cytokine-inducible SH2-containing protein</fullName>
</names>
<xref>
<primaryRef db="uniprotkb" id="Q62225" secondary="cish_mouse" version="SP_48"/>
<secondaryRef db="go" id="GO:0005886" secondary="C:plasma membrane"/>
<secondaryRef db="go" id="GO:0005515" secondary="F:protein binding"/>
<secondaryRef db="go" id="GO:0007205" secondary="P:protein kinase C activation"/>
<secondaryRef db="interpro" id="IPR000980" secondary="SH2"/>
<secondaryRef db="interpro" id="IPR001496" secondary="SOCS_C"/>
<secondaryRef db="intact" id="EBI-617489" secondary="cish_mouse"/>
</xref>
<organism ncbiTaxId="10090">
<names>
<shortLabel>mouse</shortLabel>
<fullName>Mus musculus</fullName>
</names>
</organism>
<sequence>MVLCVQGSCPLLAVEQIGRRPLWAQSLELPGPAMQPLPTGAFPEEVTEETPVQAENEPKVLDPEGDLLCIAKTFSYLRESGWYWGSITASEARQHLQKMPEGTFLVRDSTHPSYLFTLSVKTTRGPTNVRIEYADSSFRLDSNCLSRPRILAFPDVVSLVQHYVASCAADTRSDSPDPAPTPALPMSKQDAPSDSVLPIPVATAVHLKLVQPFVRRSSARSLQHLCRLV...
</proteinInteractor>
<proteinInteractor id="EBI-617737">
<names>
<shortLabel>socs2_human</shortLabel>
<fullName>Suppressor of cytokine signaling 2</fullName>
</names>
<xref>
<primaryRef db="uniprotkb" id="O14508" secondary="socs2_human" version="SP_49"/>
<secondaryRef db="go" id="GO:0005737" secondary="C:cytoplasm"/>
<secondaryRef db="go" id="GO:0005131" secondary="F:growth hormone receptor bind"/>
<secondaryRef db="go" id="GO:0005159" secondary="F:insulin-like growth factor r"/>
<secondaryRef db="go" id="GO:0008269" secondary="F:JAK pathway signal transduct"/>
<secondaryRef db="go" id="GO:0005148" secondary="F:prolactin receptor binding"/>
<secondaryRef db="go" id="GO:0005070" secondary="F:SH3/SH2 adaptor activity"/>
<secondaryRef db="go" id="GO:0006916" secondary="P:anti-apoptosis"/>
<secondaryRef db="go" id="GO:0007259" secondary="P:JAK-STAT cascade"/>
<secondaryRef db="go" id="GO:0045666" secondary="P:positive regulation of neuro"/>
<secondaryRef db="go" id="GO:0040014" secondary="P:regulation of body size"/>
<secondaryRef db="go" id="GO:0001558" secondary="P:regulation of cell growth"/>
<secondaryRef db="go" id="GO:0009966" secondary="P:regulation of signal transdu"/>
<secondaryRef db="interpro" id="IPR000980" secondary="SH2"/>
<secondaryRef db="interpro" id="IPR001496" secondary="SOCS_C"/>
<secondaryRef db="uniprotkb" id="O14542" secondary="socs2_human" version="SP_49"/>
<secondaryRef db="uniprotkb" id="O95102" secondary="socs2_human" version="SP_49"/>
<secondaryRef db="uniprotkb" id="Q9UKS5" secondary="socs2_human" version="SP_49"/>
<secondaryRef db="go" id="GO:0005515" secondary="F:protein binding"/>
<secondaryRef db="intact" id="EBI-617737" secondary="socs2_human"/>
</xref>
<organism ncbiTaxId="9606">
<names>
<shortLabel>human</shortLabel>
<fullName>Homo sapiens</fullName>
</names>
</organism>
<sequence>MTLRCLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPSLQHLCRLTINKCTGAIWGLPLPTRLKDYLEEYKFQV</sequence>
</proteinInteractor>
</interactorList>
<interactionList>
<interaction>
<names>
<shortLabel>sv40-tp53-1</shortLabel>
<fullName>Interactions between SV40 large T antigen and murine p53 demonstrated by MAPPIT</fullName>
</names>
<experimentList>
<experimentRef ref="EBI-617684"/>
</experimentList>
<participantList>
<proteinParticipant>
<proteinInteractorRef ref="EBI-617698"/>
<role>prey</role>
</proteinParticipant>
<proteinParticipant>
<proteinInteractorRef ref="EBI-474016"/>
<role>bait</role>
</proteinParticipant>
</participantList>
<interactionType>
<names>
<shortLabel>physical interaction</shortLabel>
<fullName>physical interaction</fullName>
</names>
<xref>
<primaryRef db="psi-mi" id="MI:0218"/>
<secondaryRef db="pubmed" id="14755292"/>
</xref>
</interactionType>
<xref>
<primaryRef db="intact" id="EBI-617704" secondary="sv40-tp53-1"/>
</xref>
<attributeList>
<attribute name="kd">1.0</attribute>
</attributeList>
</interaction>
<interaction>
<names>
<shortLabel>epor-cish-4</shortLabel>
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