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      <title>Partial nucleotide sequence of poplar mosaic virus RNA confirms its classification as a carlavirus.</title>
      <db_xref db="PUBMED" dbkey="1629709"/>
      <journal>J. Gen. Virol.</journal>
      <location pages="1887-90" volume="73 ( Pt 7)"/>
      <year>1992</year>
    </publication>
  </pub_list>
  <member_list>
    <db_xref protein_count="996" db="PFAM" dbkey="PF00286" name="Flexi_CP"/>
    <db_xref protein_count="955" db="PRINTS" dbkey="PR00232" name="POTXCARLCOAT"/>
    <db_xref protein_count="838" db="PROSITE" dbkey="PS00418" name="POTEX_CARLAVIRUS_COAT"/>
  </member_list>
  <external_doc_list>
    <db_xref db="PANDIT" dbkey="PF00286"/>
    <db_xref db="MSDsite" dbkey="PS00418"/>
    <db_xref db="BLOCKS" dbkey="IPB000052"/>
    <db_xref db="PROSITEDOC" dbkey="PDOC00346"/>
  </external_doc_list>
  <taxonomy_distribution>
    <taxon_data name="Virus" proteins_count="996"/>
  </taxonomy_distribution>
</interpro>
<interpro id="IPR000053" protein_count="1187" short_name="Pyrmidine_PPase" type="Family">
  <name>Pyrimidine-nucleoside phosphorylase</name>
  <abstract>
<p>Two highly similar activities are represented in this group: thymidine phosphorylase (TP, gene deoA, <db_xref db="EC" dbkey="2.4.2.4"/>) and pyrimidine-nucleoside phosphorylase (PyNP, gene pdp, <db_xref db="EC" dbkey="2.4.2.2"/>). Both are dimeric...
</abstract>
  <class_list>
    <classification id="GO:0006206" class_type="GO">
      <category>Biological Process</category>
      <description>pyrimidine base metabolic process</description>
    </classification>
  </class_list>
  <example_list>
    <example>
      <db_xref db="SWISSPROT" dbkey="A0B6C9"/>
    </example>
    <example>
      <db_xref db="SWISSPROT" dbkey="P07650"/>
    </example>
    <example>
      <db_xref db="SWISSPROT" dbkey="P19971"/>
    </example>
    <example>
      <db_xref db="SWISSPROT" dbkey="Q5FVR2"/>
    </example>
    <example>
      <db_xref db="SWISSPROT" dbkey="Q99N42"/>
    </example>
  </example_list>
  <pub_list>
    <publication id="PUB00010722">
      <author_list>Griffiths L, Stratford IJ.</author_list>
      <title>Platelet-derived endothelial cell growth factor thymidine phosphorylase in tumour growth and response to therapy.</title>
      <db_xref db="PUBMED" dbkey="9310231"/>
      <journal>Br. J. Cancer</journal>
      <location issue="6" pages="689-93" volume="76"/>
      <year>1997</year>
    </publication>
    <publication id="PUB00010723">
      <author_list>Pugmire MJ, Cook WJ, Jasanoff A, Walter MR, Ealick SE.</author_list>
      <title>Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.</title>
      <db_xref db="PUBMED" dbkey="9698549"/>
      <journal>J. Mol. Biol.</journal>
      <location issue="2" pages="285-99" volume="281"/>
      <year>1998</year>
    </publication>
    <publication id="PUB00010724">
      <author_list>Pugmire MJ, Ealick SE.</author_list>
      <title>The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation.</title>
      <db_xref db="PUBMED" dbkey="9817849"/>
      <journal>Structure</journal>
      <location issue="11" pages="1467-79" volume="6"/>
      <year>1998</year>
    </publication>
  </pub_list>
  <child_list>
    <rel_ref ipr_ref="IPR013466"/>
    <rel_ref ipr_ref="IPR018090"/>
  </child_list>
  <contains>
    <rel_ref ipr_ref="IPR000312"/>
    <rel_ref ipr_ref="IPR013102"/>
    <rel_ref ipr_ref="IPR017459"/>
    <rel_ref ipr_ref="IPR017872"/>
    <rel_ref ipr_ref="IPR020072"/>
  </contains>
  <member_list>
    <db_xref protein_count="1182" db="PANTHER" dbkey="PTHR10515" name="Pyrmidine_PPase"/>
    <db_xref protein_count="1120" db="PIRSF" dbkey="PIRSF000478" name="TP_PyNP"/>
  </member_list>
  <external_doc_list>
    <db_xref db="BLOCKS" dbkey="IPB000053"/>
    <db_xref db="EC" dbkey="2.4.2.4"/>
    <db_xref db="PROSITEDOC" dbkey="PDOC00557"/>
  </external_doc_list>
  <structure_db_links>
    <db_xref db="PDB" dbkey="1azy"/>
    <db_xref db="PDB" dbkey="1brw"/>
    <db_xref db="PDB" dbkey="1otp"/>
    <db_xref db="PDB" dbkey="1tpt"/>
    <db_xref db="PDB" dbkey="1uou"/>
    <db_xref db="PDB" dbkey="2dsj"/>
    <db_xref db="PDB" dbkey="2j0f"/>
    <db_xref db="PDB" dbkey="2tpt"/>
    <db_xref db="CATH" dbkey="1.20.970.10"/>
    <db_xref db="CATH" dbkey="3.40.1030.10"/>
    <db_xref db="CATH" dbkey="3.90.1170.30"/>
    <db_xref db="SCOP" dbkey="a.46.2.1"/>
    <db_xref db="SCOP" dbkey="c.27.1.1"/>
    <db_xref db="SCOP" dbkey="d.41.3.1"/>
  </structure_db_links>
  <taxonomy_distribution>
    <taxon_data name="Bacteria" proteins_count="1121"/>
    <taxon_data name="Archaea" proteins_count="46"/>
    <taxon_data name="Eukaryota" proteins_count="20"/>
    <taxon_data name="Chordata" proteins_count="15"/>
    <taxon_data name="Human" proteins_count="5"/>
    <taxon_data name="Mouse" proteins_count="1"/>
    <taxon_data name="Metazoa" proteins_count="17"/>
    <taxon_data name="Plastid Group" proteins_count="1"/>