BioPerl
view release on metacpan or search on metacpan
t/data/entrezgene.dat view on Meta::CPAN
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gi 51511728 } ,
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gi 51511728 } ,
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gi 51511728 } ,
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gi 51511728 } ,
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gi 51511728 } ,
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gi 51511728 } ,
int {
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gi 51511728 } ,
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id
gi 51511728 } ,
int {
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strand minus ,
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gi 51511728 } } } ,
seqs {
whole
gi 6226959 } ,
products {
{
type peptide ,
heading "Reference" ,
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genomic-coords {
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{
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gi 51511728 } ,
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t/data/entrezgene.dat view on Meta::CPAN
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t/data/entrezgene.dat view on Meta::CPAN
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type peptide ,
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gi 51471135 } ,
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gi 51471135 } ,
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t/data/entrezgene.dat view on Meta::CPAN
{
type other ,
label "Alternate name" ,
text "WIAF-1430-STS" ,
version 0 } } } ,
{
type comment ,
version 0 ,
source {
{
src {
db "UniSTS" ,
tag
id 147540 } ,
anchor "NoName" ,
post-text "(e-PCR)" } } } ,
{
type comment ,
version 0 ,
source {
{
src {
db "UniSTS" ,
tag
id 151442 } ,
anchor "NoName" ,
post-text "(e-PCR)" } } } } } ,
{
type comment ,
heading "NCBI Reference Sequences (RefSeq)" ,
version 0 ,
products {
{
type mRNA ,
heading "mRNA Sequence" ,
accession "NM_000014" ,
version 3 ,
source {
{
src {
db "Nucleotide" ,
tag
id 6226959 } ,
anchor "NM_000014" } } ,
seqs {
whole
gi 6226959 } ,
products {
{
type peptide ,
heading "Product" ,
accession "NP_000005" ,
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source {
{
src {
db "Protein" ,
tag
id 4557225 } ,
anchor "NP_000005" ,
post-text "alpha-2-macroglobulin precursor" } } ,
seqs {
whole
gi 4557225 } ,
comment {
{
type other ,
heading "Conserved Domains" ,
version 0 ,
source {
{
src {
db "PROT_CDD" ,
tag
id 4557225 } ,
pre-text "(2)" ,
anchor "summary" } } ,
comment {
{
type other ,
version 0 ,
source {
{
src {
db "CDD" ,
tag
id 5952 } ,
anchor "pfam00207: A2M; Alpha-2-macroglobulin family" } } ,
comment {
{
type other ,
text "Location: 725 - 1463 Blast Score: 2322" ,
version 0 } } } ,
{
type other ,
version 0 ,
source {
{
src {
db "CDD" ,
tag
id 25832 } ,
anchor "pfam01835: A2M_N; Alpha-2-macroglobulin
family N-terminal region" } } ,
comment {
{
type other ,
text "Location: 21 - 628 Blast Score: 1948" ,
version 0 } } } } } } } } ,
comment {
{
type other ,
heading "Source Sequence" ,
version 0 ,
source {
{
src {
db "Nucleotide" ,
tag
str "M11313" } ,
anchor "M11313" } } ,
t/data/entrezgene.dat view on Meta::CPAN
anchor "05010" ,
url "http://www.genome.jp/dbget-bin/show_pathway?hsa05010+2" } } } ,
{
type comment ,
text "KEGG pathway: Coagulation cascade" ,
version 0 ,
source {
{
src {
db "04610" ,
tag
str "04610" } ,
anchor "04610" ,
url "http://www.genome.jp/dbget-bin/show_pathway?hsa04610+2" } } } ,
{
type comment ,
text "KEGG pathway: Complement and coagulation cascades" ,
version 0 ,
source {
{
src {
db "04610" ,
tag
str "04610" } ,
anchor "04610" ,
url "http://www.genome.jp/dbget-bin/show_pathway?hsa04610+2" } } } ,
{
type comment ,
text "Reactome: Hemostasis" ,
version 0 ,
source {
{
anchor "49292" ,
url "http://www.reactome.org/cgi-bin/link?SOURCE=UniProt&ID=P010
23" } } } } } ,
{
type generif ,
text "an important involvement of alpha2M in regulation of increased
proteolytic activity occurring in multiple sclerosis disease" ,
version 0 ,
refs {
pmid 15511627 } ,
create-date
str "Dec 18 2004 10:01AM" ,
update-date
str "Dec 18 2004 1:19PM" } ,
{
type generif ,
text "alpha2-macroglobulin inhibits human pepsin and gastricsin" ,
version 0 ,
refs {
pmid 14506912 } ,
create-date
str "Oct 7 2003 12:00AM" ,
update-date
str "Jul 7 2004 1:36PM" } ,
{
type generif ,
text "There is a significant genetic association of the 5 bp deletion
and two novel polymorphisms in alpha-2-macroglobulin alpha-2-macroglobulin
precursor with AD" ,
version 0 ,
refs {
pmid 12966032 } ,
create-date
str "Jun 27 2004 5:41PM" ,
update-date
str "Jun 27 2004 6:18PM" } ,
{
type generif ,
text "Alpha2-macroglobulin is a substrate and an endogenous inhibitor
for ADAMTS-4 and ADAMTS-5" ,
version 0 ,
refs {
pmid 14715656 } ,
create-date
str "Jun 14 2004 4:41PM" ,
update-date
str "Jun 14 2004 5:44PM" } ,
{
type generif ,
text "A2M-D allele played a weak Alzheimer disease protective role, and
APOE-E4 and A2M-G alleles might act synergistically in Alzheimer disease risk
for mainland Han Chinese." ,
version 0 ,
refs {
pmid 14675603 } ,
create-date
str "Feb 17 2004 12:00AM" ,
update-date
str "Apr 13 2004 1:35PM" } ,
{
type generif ,
text "Plasma from patients homozygous for the intronic deletion (DD)
showed normal alpha(2)M subunit size, conformation, and proteinase inhibitory
activity. Plasma alpha(2)M from two DD patients showed markedly increased
TGF-beta1 binding." ,
version 0 ,
refs {
pmid 14678766 } ,
create-date
str "Jan 20 2004 12:00AM" ,
update-date
str "Mar 7 2004 7:01AM" } ,
{
type generif ,
text "The presence of MPO-G/G and A2M-Val/Val genotypes synergistically
increased the risk of AD (OR, 25.5; 95% CI, 4.65-139.75)." ,
version 0 ,
refs {
pmid 15023809 } ,
create-date
str "Mar 25 2004 12:00AM" ,
update-date
str "Apr 18 2004 7:02AM" } ,
{
type generif ,
text "alpha2-M deletion polymorphism is probably not associated with
functional deficiencies important in Alzheimer's disease pathology" ,
version 0 ,
refs {
t/data/entrezgene.dat view on Meta::CPAN
version 0 ,
refs {
pmid 12015318 } ,
create-date
str "Sep 5 2002 12:00AM" ,
update-date
str "Sep 23 2002 6:27AM" } ,
{
type generif ,
text "has an important role in the AD-specific neurodegenerative process
but its exon 24 Val-1000-Ile polymorphism is not likely to be associated with
late-onset sporadic AD in the Hungarian population" ,
version 0 ,
refs {
pmid 11901360 } ,
create-date
str "Aug 6 2002 12:00AM" ,
update-date
str "Aug 28 2002 6:15PM" } ,
{
type generif ,
text "REVIEW: binds and neutralizes alfimeprase, which has direct
proteolytic activity against the fibrinogen Aalpha chain" ,
version 0 ,
refs {
pmid 11910179 } ,
create-date
str "Jun 12 2002 12:00AM" ,
update-date
str "Sep 7 2003 7:01AM" } ,
{
type generif ,
text "distinct binding sites mediate interaction with beta-amyloid
peptide and growth factors" ,
version 0 ,
refs {
pmid 11823454 } ,
create-date
str "May 4 2002 12:00AM" ,
update-date
str "May 18 2002 6:08AM" } ,
{
type generif ,
text "Differential binding to ldl receptor related protein" ,
version 0 ,
refs {
pmid 11811950 } ,
create-date
str "Feb 14 2002 12:00AM" ,
update-date
str "Mar 4 2002 7:46AM" } ,
{
type generif ,
heading "HIV-1 protein interactions" ,
version 0 ,
comment {
{
type generif ,
text "Binding of HIV-1 Tat to LRP inhibits neuronal binding, uptake
and degradation of physiological ligands for LRP, including
alpha2-macroglobulin, apolipoprotein E4, amyloid precursor and amyloid
beta-protein" ,
version 0 ,
refs {
pmid 11100124 } ,
comment {
{
type comment ,
label "Tat" ,
accession "NP_057853" ,
version 1 ,
source {
{
src {
db "GeneID" ,
tag
id 155871 } } } } ,
{
type comment ,
accession "NP_000005" ,
version 1 } } ,
create-date
str "May 11 2004 12:48PM" ,
update-date
str "May 11 2004 1:10PM" } } } } ,
unique-keys {
{
db "LocusID" ,
tag
id 2 } ,
{
db "MIM" ,
tag
id 103950 } } ,
xtra-index-terms {
"LOC2" } ,
xtra-properties {
{
tag "PROP" ,
value "phenotype" } } }
Entrezgene ::= {
track-info {
geneid 3 ,
status live ,
create-date
std {
year 2003 ,
month 8 ,
day 28 ,
hour 20 ,
minute 30 ,
second 0 } ,
update-date
std {
year 2005 ,
month 2 ,
day 17 ,
hour 12 ,
minute 9 ,
second 0 } } ,
type pseudo ,
t/data/entrezgene.dat view on Meta::CPAN
map-type cyto } } ,
gene-source {
src "LocusLink" ,
src-int 12 ,
src-str2 "12" ,
gene-display FALSE ,
locus-display FALSE ,
extra-terms FALSE } ,
locus {
{
type genomic ,
heading "Reference" ,
accession "NC_000014" ,
version 7 ,
seqs {
int {
from 94150523 ,
to 94160143 ,
strand plus ,
id
gi 51511730 } } ,
products {
{
type mRNA ,
heading "Reference" ,
accession "NM_001085" ,
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gi 51511730 } ,
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gi 51511730 } ,
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gi 51511730 } } } ,
seqs {
whole
gi 9665246 } ,
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type peptide ,
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gi 51511730 } } } ,
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{
type genomic ,
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int {
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gi 51493278 } } ,
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{
type mRNA ,
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gi 9665246 } ,
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type peptide ,
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gi 51493278 } } } ,
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gi 4501843 } } } } } } ,
{
type genomic ,
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int {
from 23153523 ,
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id
gi 51472322 } } ,
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{
type mRNA ,
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gi 9665246 } ,
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type peptide ,
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gi 51472322 } } } ,
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gi 4501843 } } } } } } } ,
properties {
{
type comment ,
label "Nomenclature" ,
version 0 ,
source {
{
anchor "HUGO Gene Nomenclature Committee" } } ,
properties {
{
type property ,
label "Official Symbol" ,
text "SERPINA3" ,
version 0 } ,
{
type property ,
label "Official Full Name" ,
text "serine (or cysteine) proteinase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 3" ,
version 0 } } } ,
{
type comment ,
heading "GeneOntology" ,
version 0 ,
source {
{
pre-text "Provided by" ,
anchor "GOA" ,
url "http://www.ebi.ac.uk/GOA/" } } ,
t/data/entrezgene.dat view on Meta::CPAN
version 0 ,
source {
{
src {
db "UniSTS" ,
tag
id 86678 } ,
anchor "RH91507" ,
post-text "(e-PCR)" } } ,
comment {
{
type other ,
label "Alternate name" ,
text "stSG44830" ,
version 0 } } } ,
{
type comment ,
version 0 ,
source {
{
src {
db "UniSTS" ,
tag
id 272387 } ,
anchor "PMC27764P1" ,
post-text "(e-PCR)" } } } } } ,
{
type comment ,
heading "NCBI Reference Sequences (RefSeq)" ,
version 0 ,
products {
{
type mRNA ,
heading "mRNA Sequence" ,
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source {
{
src {
db "Nucleotide" ,
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id 50659079 } ,
anchor "NM_001085" } } ,
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whole
gi 50659079 } ,
products {
{
type peptide ,
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accession "NP_001076" ,
version 2 ,
source {
{
src {
db "Protein" ,
tag
id 50659080 } ,
anchor "NP_001076" ,
post-text "serine (or cysteine) proteinase inhibitor, clade
A, member 3 precursor" } } ,
seqs {
whole
gi 50659080 } ,
comment {
{
type other ,
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version 0 ,
source {
{
src {
db "PROT_CDD" ,
tag
id 50659080 } ,
pre-text "(1)" ,
anchor "summary" } } ,
comment {
{
type other ,
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source {
{
src {
db "CDD" ,
tag
id 28234 } ,
anchor "cd02056: alpha-1-antitrypsin_like;
alpha-1-antitrypsin_like" } } ,
comment {
{
type other ,
text "Location: 52 - 417 Blast Score: 1367" ,
version 0 } } } } } } } } ,
comment {
{
type other ,
heading "Source Sequence" ,
version 0 ,
source {
{
src {
db "Nucleotide" ,
tag
str "BC003559,BG565041" } ,
anchor "BC003559,BG565041" } } ,
comment {
{
type other ,
version 0 } } } } } } } ,
{
type comment ,
heading "Related Sequences" ,
version 0 ,
products {
{
type genomic ,
heading "Genomic" ,
accession "X00947" ,
version 1 ,
source {
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