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 <table cellpadding="0" cellspacing="0" width="100%"><tr><th colspan="2">Entry information</th></tr> <tr><td width="20%">Entry name</td> <td><strong>DNP_DENAN</strong></td></tr> <tr><td>Primary accession</td> <td><strong>P28374</strong></td></tr> <tr...
 cGMP via the natriuretic peptide receptor A (NPR1). Is a poor
 agonist of the atrial natriuretic peptide receptor B (NPR2). Is
 not degradated by neutral endopeptidase (NEP / MME). Binds to
 atrial natriuretic peptide clearance receptor (NPR3 / NPR-C),
 which may be responsible of the removal of DNP from the
 circulation. Increases calcium uptake and induces histamine
 release from rat peritoneal mast cells. Increases calcium-
 activated potassium current in gastric antral circular smooth
 muscle cells by increasing cGMP production and activating inositol
 trisphosphate receptors (IP3Rs).
</td></tr> <tr><td>subcellular location</td> <td class="sub_entry">Secreted.</td></tr> <tr><td>tissue specificity</td> <td class="sub_entry">Expressed by the venom gland.</td></tr> <tr><td>similarity</td> <td class="sub_entry">Belongs to the natriure...