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[Term]
id: MI:0898
name: putative self
def: "Molecule that is reported to self-interact but the experimental condition does not allow to resolve whether the interaction is intramolecular (true self interaction) or intermolecular (homodimer)." [PMID:14755292]
subset: PSI-MI slim
is_a: MI:0495 ! experimental role
is_a: MI:0500 ! biological role

[Term]
id: MI:0899
name: p3 filamentous phage display
def: "pIII is one of the minor coat proteins that decorates in five copies the emerging tip of filamentous phage. Similarly to pVIII pIII also tolerates peptide insertions at the amino-terminus. The sequences to be displayed can either be encoded in ...
subset: PSI-MI slim
synonym: "low valency display" EXACT PSI-MI-alternate []
synonym: "p3 filamentous phage" EXACT PSI-MI-short []
is_a: MI:0048 ! filamentous phage display

[Term]
id: MI:0900
name: p8 filamentous phage display
def: "pVIII is the major coat protein of filamentous phage. Its amino-terminus is exposed to solvent and tolerates the insertion of relatively large peptide fragments. By inserting the peptide coding sequence into the phage copy of the pVIII gene up ...
subset: PSI-MI slim
synonym: "high valency display" EXACT PSI-MI-alternate []
synonym: "p8 filamentous phage" EXACT PSI-MI-short []
is_a: MI:0048 ! filamentous phage display

[Term]
id: MI:0901
name: isotope label footprinting
def: "Exposed amino acid residues undergo a rapid exchange of a specific radio-isotope e.g. hydrogen/deuterium. Residues involved in a molecular interaction are protected from this exchange and exhibit a much slower rate of exchange. This method of b...
subset: PSI-MI slim
synonym: "isotope footprinting" EXACT PSI-MI-short []
is_a: MI:0605 ! enzymatic footprinting

[Term]
id: MI:0902
name: rna cleavage
def: "Any process by which an RNA molecule is cleaved at specific sites or in a regulated manner." [GO:0006396, PMID:14681407]
subset: PSI-MI slim
is_a: MI:0910 ! nucleic acid cleavage

[Term]
id: MI:0903
name: mpidb
def: "The microbial protein-protein interactions database (MPDIB) aims to collect and provide all known physical prokaryotic interactions." [PMID:14755292]
subset: PSI-MI slim
synonym: "MPDIB" EXACT PSI-MI-alternate []
is_a: MI:0461 ! interaction database

[Term]
id: MI:0904
name: polysaccharide
def: "A polysaccharide is a complex polymer of carbohydrate monormers. They are polymers made up of many monosaccharides joined together by glycosidic bonds. They are therefore very large, often branched, macromolecules." [PMID:14755292]
subset: PSI-MI slim
is_a: MI:0383 ! biopolymer

[Term]
id: MI:0905
name: amplified luminescent proximity homogeneous assay
def: "AlphaScreen relies on the use of Donor and Acceptor beads that are coated with a layer of hydrogel providing functional groups for bioconjugation. When a biological interaction between molecules brings the beads into proximity, a cascade of che...
subset: PSI-MI slim
synonym: "alfa-screen" EXACT PSI-MI-short []
synonym: "AlphaScreen" EXACT PSI-MI-alternate []
is_a: MI:0013 ! biophysical

[Term]
id: MI:0906
name: au1 tag
def: "The protein of interest is expressed as a fusion to the peptide DTYRYI for which antibodies are commercially available." [PMID:18216269]
subset: PSI-MI slim
synonym: "DTYRYI epitope tag" EXACT PSI-MI-alternate []
is_a: MI:0507 ! tag

[Term]
id: MI:0907
name: conformational status
def: "Statement about the native/denatured conformation of the protein." [PMID:14755292]
subset: PSI-MI slim
synonym: "conformation" EXACT PSI-MI-short []
is_a: MI:0346 ! experimental preparation

[Term]
id: MI:0908
name: denatured
def: "Altered conformation state of the protein as a result of heat or chemical modification resulting in a changed structure of the protein." [PMID:14755292]
subset: PSI-MI slim
is_a: MI:0907 ! conformational status

[Term]
id: MI:0909
name: native
def: "State of the protein without interference i.e. the natural form." [PMID:14755292]
subset: PSI-MI slim
is_a: MI:0907 ! conformational status

[Term]
id: MI:0910
name: nucleic acid cleavage
def: "Covalent bond breakage of a nucleic acid molecule leading to the formation of smaller fragments." [PMID:14755292]
subset: PSI-MI slim
synonym: "ncl acid cleavage" EXACT PSI-MI-short []
is_a: MI:0194 ! cleavage reaction

[Term]
id: MI:0911
name: cross linker
def: "A variety of crosslinkers are used to analyze subunit structure of proteins, protein interactions and various parameters of protein function. Subunit structure is deduced since crosslinkers only bind surface amino residues in relatively close p...
subset: PSI-MI slim
synonym: "crosslinker" EXACT PSI-MI-alternate []
is_a: MI:0505 ! experimental feature

[Term]
id: MI:0912
name: spdp cross linker
def: "N -Succinimidyl 3-(2-pyridyldithio)-propionate, is heterobifunctional, thiol-cleavable \nand membrane permeable crosslinkers. It contains an amine-reactive N-hydroxysuccinimide (NHS) ester \nthat will react with lysine residues to form a stable...
subset: PSI-MI slim
synonym: "N -Succinimidyl 3-(2-pyridyldithio)-propionate" EXACT PSI-MI-alternate []
is_a: MI:0911 ! cross linker

[Term]