AI-Gene-Sequence

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AI/Gene/Sequence.pm  view on Meta::CPAN

package AI::Gene::Sequence;
require 5.6.0;
use strict;
use warnings;

BEGIN {
  use Exporter   ();
  our ($VERSION, @ISA, @EXPORT, @EXPORT_OK, %EXPORT_TAGS);
  $VERSION     = 0.22;
  @ISA         = qw(Exporter);
  @EXPORT      = ();
  %EXPORT_TAGS = ();
  @EXPORT_OK   = qw();
}
our @EXPORT_OK;

my ($probs,$mut_keys) = _normalise( { map {$_ => 1} 
				      qw(insert remove overwrite 
					 duplicate minor major 
					 switch shuffle reverse) } );

##
# calls mutation method at random
# 0: number of mutations to perform
# 1: ref to hash of probs to use (otherwise uses default mutations and probs)

sub mutate {
  my $self = shift;
  my $num_mutates = +$_[0] || 1;
  my $rt = 0;
  my ($hr_probs, $muts);
  if (ref $_[1] eq 'HASH') { # use non standard mutations or probs
    ($hr_probs, $muts) = _normalise($_[1]);
  }
  else {                     # use standard mutations and probs
    $hr_probs = $probs;
    $muts = $mut_keys;
  }

 MUT_CYCLE: for (1..$num_mutates) {
    my $rand = rand;
    foreach my $mutation (@{$muts}) {
      next unless $rand < $hr_probs->{$mutation};
      my $mut = 'mutate_' . $mutation;
      $rt += $self->$mut(1);
      next MUT_CYCLE;
    }
  }
  return $rt;
}

##
# creates a normalised and cumulative prob distribution for the
# keys of the referenced hash

sub _normalise {
  my $hr = $_[0];
  my $h2 = {};
  my $muts = [keys %{$hr}];
  my $sum = 0;
  foreach (values %{$hr}) {
    $sum += $_;
  }
  if ($sum <= 0) {
    die "Cannot randomly mutate with bad probability distribution";
  }
  else {
    my $cum;
    @{$h2}{ @{$muts} } = map {$cum +=$_; $cum / $sum} @{$hr}{ @{$muts} };
    return ($h2, $muts);
  }
}

##
# inserts one element into the sequence
# 0: number to perform ( or 1)
# 1: position to mutate (undef for random)

sub mutate_insert {
  my $self = shift;
  my $num = +$_[0] || 1;
  my $rt = 0;
  for (1..$num) {
    my $length = length $self->[0];
    my $pos = defined($_[1]) ? $_[1] : int rand $length;



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