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    }
    else {
        open $out_fh, ">", $opt->{outfile};
    }
 
    my $desc .= <<MARKDOWN;
 
* [lav format](http://www.bx.psu.edu/miller_lab/dist/lav_format.html)
 
    Here <start> and <stop> are origin 1 (i.e. the first base in the original
    given sequence is called '1') and inclusive (both endpoints are included
    in the interval).
 
* [psl format](https://genome.ucsc.edu/FAQ/FAQformat.html#format2)
 
    Be aware that the coordinates for a negative strand in a PSL line are
    handled in a special way. In the qStart and qEnd fields, the coordinates
    indicate the position where the query matches from the point of view of
    the forward strand, even when the match is on the reverse strand.
    However, in the qStarts list, the coordinates are reversed.