App-GeoCancerPrognosticDatasetsRetriever
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data/bladder_cancer_GEO.txt view on Meta::CPAN
28. Super-enhancer LncRNA expression profile in human bladder cancer cell line and human urothelial immortalized cell line
(Submitter supplied) To further explore the differential expression profile of super-enhancer long noncoding RNA (LncRNA) in human bladder cancer, we have employed super-enhancer lncRNA microarray expression profiling as a discovery platform to ident...
Organism: Homo sapiens
Type: Expression profiling by array; Non-coding RNA profiling by array
Platform: GPL24592 2 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE159nnn/GSE159682/
Series Accession: GSE159682 ID: 200159682
29. RBMX suppresses tumorigenicity and progression of bladder cancer via interaction with hnRNP A1 protein to regulate PKM alternative splicing
(Submitter supplied) Bladder cancer (BCa) is one of the most common malignant tumors of urinary system and has high incidence rate and mortality but there is a lack of effective treatment. Therefore, an in-depth study of the molecular mechanisms invo...
Organism: Homo sapiens
Type: Expression profiling by high throughput sequencing
Platform: GPL24676 6 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE150nnn/GSE150548/
SRA Run Selector: https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA632747
Series Accession: GSE150548 ID: 200150548
30. Next Generation Sequencing Quantitative Analysis of altered expression of genes in lncRNA ELNAT1 knockdown bladder cancer cells
(Submitter supplied) Bladder cancer (BCa) is one of the most common genitourinary malignancies worldwide, with a high recurrence and mortality rate. Previous study revealed that EV-packaged ELNAT1 played an important role in the occurrence and develo...
Organism: Homo sapiens
data/bladder_cancer_GEO.txt view on Meta::CPAN
67. Genome-wide transcriptome analysis of PAK4 inhibition/knockdown in human bladder cancer cell line VMCUB1
(Submitter supplied) Using multi-omic analyses, we identified PAK4 (P21 (RAC1) Activated Kinase 4) amplification and overexpression of Kinase PAK4 in a subset of bladder cancers. We confirmed the role of PAK4 in bladder cancer cell proliferation and ...
Organism: Homo sapiens
Type: Expression profiling by high throughput sequencing
Platform: GPL16791 4 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE130nnn/GSE130455/
SRA Run Selector: https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA540285
Series Accession: GSE130455 ID: 200130455
68. Expression data from mice bladder with MB49-induced cancer treated with alpha1-oleate.
(Submitter supplied) Potent chemotherapeutic agents are required to counteract the aggressive behavior of cancer cells and patients often experience severe side effects, due to tissue toxicity. This study addresses if a better balance between efficac...
Organism: Mus musculus
Type: Expression profiling by array
Platform: GPL11180 9 Samples
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE148nnn/GSE148308/
Series Accession: GSE148308 ID: 200148308
69. Next Generation Sequencing Facilitates Quantitative Analysis of bladder cancer cells (T24) with constitutively active RhoC mutant (Q63E) overexpression and vector control (VEC) Transcriptomes
(Submitter supplied) Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare NGS-derived constitutively active RhoC mutant (Q63E) overexpressed bladder cancer ce...
Organism: Homo sapiens
Type: Expression profiling by high throughput sequencing
Platform: GPL20795 6 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE129nnn/GSE129295/
SRA Run Selector: https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA530762
Series Accession: GSE129295 ID: 200129295
70. Elucidating the role of glycogen debranching enzyme AGL in bladder carcinogenesis by generation and characterization of knockout mice
(Submitter supplied) Amylo-alpha-1-6-glucosidase-4-alpha-glucanotransferase (AGL) is an enzyme primarily responsible for glycogen debranching. Inactivating germline mutations lead to glycogen storage disease III (GSDIII). AGL was found to be a tumor ...
Organism: Mus musculus
Type: Expression profiling by high throughput sequencing
Platform: GPL21103 8 Samples
FTP download: GEO (BW, TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE113nnn/GSE113158/
SRA Run Selector: https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA450320
Series Accession: GSE113158 ID: 200113158
71. Genomic Landscape of Young-Onset Bladder Cancer and Its Prognostic Implication on Adult Bladder Cancer
(Submitter supplied) Bladder cancer is common in elderly men, and it is a highly mutated tumor with frequent TP53 and FGFR3 mutation. Young-onset bladder cancer (YBC) is extremely rare; therefore, its genomic characteristics are unknown and appropria...
data/bladder_cancer_GEO.txt view on Meta::CPAN
117. Genomic Whole-Organ Map of Mucosal Field Effects Initiating Human Bladder Carcinogenesis
(Submitter supplied) We have developed a whole organ mapping approach which combines microscopic assessment of the entire mucosal membrane of the organ affected by cancer with comprehensive genomic profiling. It was used to study the chronology of t...
Organism: Homo sapiens
Type: SNP genotyping by SNP array; Genome variation profiling by SNP array; Methylation profiling by high throughput sequencing
Platforms: GPL26040 GPL9886 61 Samples
FTP download: GEO (IDAT, TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE125nnn/GSE125286/
Series Accession: GSE125286 ID: 200125286
118. Inhibition of a G9a/DNMT network triggers an immune-mediated bladder cancer regression treated with CM272 (IC50)
(Submitter supplied) Based on the identification of G9a as a potential target in BC, we decided to test the effect of a recently described dual inhibitor against G9a/DNMTs, CM-272, in several BC cell lines
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL17586 12 Samples
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE115nnn/GSE115544/
Series Accession: GSE115544 ID: 200115544
119. Inhibition of a G9a/DNMT network triggers an immune-mediated bladder cancer regression
(Submitter supplied) Using a novel immunocompetent quadruple (PtenF/F; Trp53F/F; Rb1F/F;Rbl1-/-) knockout transgenic mouse model of highly aggressive metastatic muscle-invasive BC, we demonstrate that treatment with CM272 and CDDP results in a signif...
Organism: Mus musculus
Type: Expression profiling by array
data/bladder_cancer_GEO.txt view on Meta::CPAN
120. Application of a NanoString Technology-based TP53 Functional Assay for Prediction of Chemotherapy Response of Muscle-invasive Bladder Cancer
(Submitter supplied) Platinum-based treatment (e.g., cisplatin, carboplatin) is generally the first-line chemotherapy for muscle-invasive bladder cancer (MIBC) and mediates regression in approximately 50% of the patients. The goal of this study was t...
Organism: Homo sapiens
Type: Other
Platform: GPL21779 48 Samples
FTP download: GEO (RCC) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE80nnn/GSE80711/
Series Accession: GSE80711 ID: 200080711
121. Expression data from T24 cells after TRIP13 knockdown
(Submitter supplied) TRIP13 is a crucial regulator of double-stranded break repair and spindle apparatus checkpoint and its abnormal expression has been found in several human cancers, whereas the role of TRIP13 in the malignant development of urothe...
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL15207 6 Samples
FTP download: GEO (CEL, XLSX) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE109nnn/GSE109029/
Series Accession: GSE109029 ID: 200109029
122. Divergent biological response to neoadjuvant chemotherapy in muscle-invasive bladder cancer
(Submitter supplied) Despite cisplatin-based neoadjuvant chemotherapy (NAC) 60% of patients with muscle-invasive bladder cancer still have residual invasive disease at radical cystectomy (RC). The NAC-induced biological alterations in these cisplatin...
Organism: Homo sapiens
Type: Expression profiling by array
data/bladder_cancer_GEO.txt view on Meta::CPAN
135. Discordant molecular subtype classification of muscle-invasive bladder cancer and matched lymph-node metastases occurs preferentially in the Basal/Squamous-like subtype.
(Submitter supplied) By combining molecular pathology, mRNA profiling, and exome-sequencing we describe muscle-invasive bladder tumors and matched lymph-node metastases.
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL6244 28 Samples
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE101nnn/GSE101723/
Series Accession: GSE101723 ID: 200101723
136. Expression data for T24 bladder cancer cell line - scrambled, SOX4-KD and SOX4 overexpression
(Submitter supplied) We knocked down SOX4 in T24 cell and created 3 cell lines: T24-scrambled, T24-SOX4-knockdown and T24-SOX4-rescue and compared gene expression changes SOX4 is a developmental transcription factor that is overexpressed in as many a...
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL23126 10 Samples
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE118nnn/GSE118572/
Series Accession: GSE118572 ID: 200118572
137. Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancerÂ
(Submitter supplied) RNA-seq was used to identify basal and luminal subtypes in canine bladder cancer. In addition to larger gene-sets, a smaller panel of genes was developed to stratify canine samples into either basal or luminal subtype prospective...
Organism: Canis lupus familiaris
Type: Expression profiling by high throughput sequencing
data/bladder_cancer_GEO.txt view on Meta::CPAN
143. Expression data from human T24 cells transfected with siNC or siNF90
(Submitter supplied) NF90 is a double-stranded RNA binding protein that takes part in microRNA biogenesis, as a competitor for the association of the microprocessor complex with pri-miRNAs, leading to a decrease in miRNA production. We want to know w...
Organism: synthetic construct; Homo sapiens
Type: Non-coding RNA profiling by array
Platform: GPL19117 4 Samples
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE82nnn/GSE82024/
Series Accession: GSE82024 ID: 200082024
144. Trancriptional profiling of rat bladder after daily administration of Pioglitazone and Rosiglitazone in vivo (miRNA)
(Submitter supplied) The purpose of the study was to investigate the nongenotoxic carcinogenic effect of Pioglitazone. Pioglitazone is a PPARgamma agonist and is known to cause bladder tumours in male rats and an increase in the incidence of bladder ...
Organism: Rattus norvegicus
Type: Non-coding RNA profiling by array
Platform: GPL14860 119 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE68nnn/GSE68604/
Series Accession: GSE68604 ID: 200068604
145. Trancriptional profiling of rat bladder after daily administration of Pioglitazone and Rosiglitazone in vivo (mRNA)
(Submitter supplied) The purpose of the study was to investigate the nongenotoxic carcinogenic effect of Pioglitazone. Pioglitazone is a PPARgamma agonist and is known to cause bladder tumours in male rats and an increase in the incidence of bladder ...
Organism: Rattus norvegicus
Type: Expression profiling by array
Platform: GPL15084 119 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE68nnn/GSE68592/
Series Accession: GSE68592 ID: 200068592
146. Cell-free lncRNA expression signatures in urine serve as novel noninvasive biomarkers for diagnosis and recurrence prediction of bladder cancer
(Submitter supplied) To identify lncRNAs dysregulated in BC, we assessed the lncRNA expression profile in pooled urine samples of 10 BC patients and 10 controls by microarray. A total of 3093 lncRNAs determined differential expression (fold change>=2...
Organism: Homo sapiens
Type: Expression profiling by array; Non-coding RNA profiling by array
data/bladder_cancer_GEO.txt view on Meta::CPAN
Series Accession: GSE76211 ID: 200076211
177. Expression profiles of circular RNAs in bladder cancer
(Submitter supplied) To explore circular RNA (circRNA) expression profiling and their biological functions in bladder cancer, we surveyed the circRNA expression signature of 4 pairs of matched bladder cancer and para-cancer tissues from clinical pati...
Organism: Homo sapiens
Type: Non-coding RNA profiling by array
Platform: GPL19978 8 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE92nnn/GSE92675/
Series Accession: GSE92675 ID: 200092675
178. Targeting metastasis stem cells through the fatty acid receptor CD36 (DID+, DID- and CD44DIM).
(Submitter supplied) Metastasis is the leading cause of cancer-related deaths. For most human cancers, the identity of the cells that initiate and promote metastasis is still unknown, hampering our ability to develop therapies to prevent or inhibit t...
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL17077 15 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE83nnn/GSE83346/
Series Accession: GSE83346 ID: 200083346
179. Targeting metastasis stem cells through the fatty acid receptor CD36
(Submitter supplied) Metastasis is the leading cause of cancer-related deaths. For most human cancers, the identity of the cells that initiate and promote metastasis is still unknown, hampering our ability to develop therapies to prevent or inhibit t...
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL17077 13 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE83nnn/GSE83276/
Series Accession: GSE83276 ID: 200083276
180. Targeting metastasis stem cells through the fatty acid receptor CD36 (II)
(Submitter supplied) Metastasis is the leading cause of cancer-related deaths. For most human cancers, the identity of the cells that initiate and promote metastasis is still unknown, hampering our ability to develop therapies to prevent or inhibit t...
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL15207 10 Samples
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE72nnn/GSE72938/
Series Accession: GSE72938 ID: 200072938
181. Targeting metastasis stem cells through the fatty acid receptor CD36 (I)
(Submitter supplied) Metastasis is the leading cause of cancer-related deaths. For most human cancers, the identity of the cells that initiate and promote metastasis is still unknown, hampering our ability to develop therapies to prevent or inhibit t...
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL16699 15 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE72nnn/GSE72935/
Series Accession: GSE72935 ID: 200072935
182. Differentially expressed mRNAs in bladder cancer stem cells
(Submitter supplied) Using the highly sensitive lncRNA array (Arraystar human lncRNA microarray), we screened the lncRNAs and mRNA abundant in bladder cancer stem cells sorted from three bladder cancer cell lines, compared to the bladder cancer cells...
Organism: Homo sapiens
data/bladder_cancer_GEO.txt view on Meta::CPAN
183. Enzalutamide inhibits proliferation of gemcitabine-resistant bladder cancer cells with increased androgen receptor expression
(Submitter supplied) Advanced bladder cancer is treated mainly with gemcitabine and cisplatin, but most patients eventually become resistance to these chemotherapeutic agents. Androgen receptor (AR) signaling has been implicated in bladder cancer as ...
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL17077 6 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE77nnn/GSE77883/
Series Accession: GSE77883 ID: 200077883
184. Gene expression analysis on arsenic-induced malignant transformation
(Submitter supplied) Arsenic is environmental risk factor and has been linked to urothelial carcinoma incidence. Arsenic exposure-induced malignant transformed cells was established from normal urothelial cells by chronic arsenic exposure for 10 mon...
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL10558 5 Samples
FTP download: GEO (IDAT, TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE90nnn/GSE90023/
Series Accession: GSE90023 ID: 200090023
185. A polymorphic intronic enhancer at 19q12 drives CCNE1 expression in bladder cancer cells
(Submitter supplied) We performed chromatin immunoprecipitation against a marker of active regulatory elements in bladder cancer cell lines to highlight regulatory regions specific to the bladder cancer genome. We then compared our dataset to other p...
Organism: Homo sapiens
Type: Genome binding/occupancy profiling by high throughput sequencing
data/bladder_cancer_GEO.txt view on Meta::CPAN
258. mRNA expression of cancer and matched adjacent tissues of 7 testicular germ cell tumors and 10 transitional cell carcinomas of bladder
(Submitter supplied) Genome-wide gene expression profile using deep sequencing technologies can drive the discovery of cancer biomarkers and therapeutic targets. Such efforts are often limited to profiling the expression signature of either mRNA or m...
Organism: Homo sapiens
Type: Expression profiling by high throughput sequencing
Platform: GPL9115 34 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE31nnn/GSE31614/
SRA Run Selector: https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA154991
Series Accession: GSE31614 ID: 200031614
259. Leukocyte-adjusted epigenome-wide association studies of blood from solid tumor patients
(Submitter supplied) Epigenome-wide association study (EWAS) of blood samples from a case-control study of bladder cancer. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately ...
Organism: Homo sapiens
Type: Methylation profiling by array
Platform: GPL8490 428 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE50nnn/GSE50409/
Series Accession: GSE50409 ID: 200050409
260. Bladder cancer: analysis of miRNA-mRNA interactions
(Submitter supplied) Background: MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Their abilyty to affect multiple gene pathways by targeting to various mRNAs makes them to an interesting class of regulators. The interplay ...
Organism: Homo sapiens
Type: Expression profiling by array; Non-coding RNA profiling by array
data/bladder_cancer_GEO.txt view on Meta::CPAN
323. microRNA-101 represses EZH2 in cancer
(Submitter supplied) To determine the phenotypic overlap between restoring miR-101 expression in bladder cancer cells and knocking down EZH2.
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL5799 12 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE13nnn/GSE13674/
Series Accession: GSE13674 ID: 200013674
324. J82 human bladder cell line treated with frankincense oil
(Submitter supplied) Frankincense oil is prepared from aromatic hardened wood resin obtained by tapping Boswellia trees. For thousands of years, it has been important both socially and economically as an ingredient in incense and perfumes. Frankinc...
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL6883 5 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE14nnn/GSE14002/
Series Accession: GSE14002 ID: 200014002
325. Array Comparative Genomic Hybridization of Merkel Cell Carcinoma Tumors
(Submitter supplied) Array-CGH profiles of Merkel cell carcinoma tumors Keywords: fresh frozen and formalin fixed paraffin embedded primary tumor, nodal and metastasis merkel cell carcinoma tumor samples
Organism: Homo sapiens
Type: Genome variation profiling by genome tiling array
Platform: GPL2879 25 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE13nnn/GSE13239/
Series Accession: GSE13239 ID: 200013239
326. Gene expression analysis of whole blood samples from patients with single and double primary tumors and healthy controls
(Submitter supplied) RNA samples from the blood of patients with double tumors, single tumors and from healthy control subjects are studied by gene expression analysis using the whole genome microarray platform AB1700 from Applied Biosystems. Gene...
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL2986 62 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE11nnn/GSE11545/
Series Accession: GSE11545 ID: 200011545
327. Comparison of Normal Prostate Fibroblasts Overexpressing Cyclin D1 and Carcinoma Associated Fibroblasts
(Submitter supplied) The cyclin D1 oncogene encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the Rb protein and promotes progression through G1 to S phase of the cell cycle. Several prostate cancer cell lines and a s...
Organism: Homo sapiens
Type: Expression profiling by array
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